![]() Implementing home blood pressure monitoring into clinical practice. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. ![]() Systemic hypertension: Mechanisms, diagnosis, and treatment. They are usually prescribed for those whose high blood pressure is difficult to control or who have diabetes or heart failure. Aldosterone antagonists block the hormone aldosterone, which sometimes causes salt and fluid retention, contributing to high blood pressure. These medications are often used with other drugs, such as a diuretic. As a result, blood flows more easily and the heart doesn't have to pump as hard. These medications prevent the muscles in the veins and arteries from tightening and narrowing. As a result, the heart doesn't pump as hard and the blood flows more easily through the veins and arteries. These medications prevent the brain from sending signals to the nervous system to speed up the heart rate and narrow the blood vessels. ![]() They might be prescribed if you have high blood pressure and are at risk of heart failure. Alpha-beta blockers work similarly to beta blockers. Alpha blockers prevent the hormone norepinephrine (noradrenaline) from tightening the muscles in the walls of smaller arteries and veins, which causes the vessels to remain open and relaxed. If you're not able to reach your blood pressure goal with one or more of the above medications, other drugs that lower blood pressure include:
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